Multiple sclerosis research could help repair damage affecting nerves

Paran Culanathan



Summary:
           A new study allows us to understand how myelin sheaths can regenerate around nerve fibers in the brain. Myelin sheaths are responsible for quick transmission of nerve signals enabling vision, sensation, and movement, but are unavailable to people with multiple sclerosis. The study found that macrophages, which are immune cells, trigger the regeneration of myelin sheaths. Researchers also found that as a result of damage to myelin, macrophages can activate a compound called activin-A, which activates production of more myelin. Scientists plan to further research how activin-A works and whether it can altered to increase its effects. This could result in a new way to slow down the progression of multiple sclerosis.



Connection: This article connects to our unit about humans. This also connects to our study of the nervous system. We learned about how the myelin sheath insulates the axons of a neuron and increases the speed at which nerve signals travel. This also connects to homeostasis because homeostasis cannot be maintained if myelin is broken down by multiple sclerosis.


Author: University of Edinburgh
Date: July 21, 2013

http://www.sciencedaily.com/releases/2013/07/130721161747.htm